The San Francisco 49ers and Los Angeles Rams have aspirations of winning the NFC West and making another Super Bowl run, but both are dealing with significant losses on offense entering Week 3 when they go head-to-head.

NFL season is cruising into Week 3. ESPN's "Monday Night Football" is back with play-by-play announcer Joe Buck and analyst Troy Aikman. Two fiery matchups are on this week's docket. Trevor Lawrence and the Jacksonville Jaguars face off against Josh Allen and the Buffalo Bills.

Bills edge rusher Von Miller is trying to keep the mood chill in Buffalo by reminding his teammates not to get ahead of themselves following a better-than-expected 2-0 start

Two AFC teams headed in opposite directions will meet on "Monday Night Football" when the Buffalo Bills (2-0) host the Jacksonville Jaguars (0-2). It's been a frustrating start offensively for Trevor Lawrence and company,

The Buffalo Bills roll on in their 2024 regular season journey with a matchup at home against the Jacksonville Jaguars at Highmark Stadium.

No Bills football this weekend as Orchard Park hosts the Jaguars for Monday Night Football. While our local weather for the last 10 days or so has been remarkably consistent, this Monday vs. a Sunday game will have implications from a weather standpoint.

Here are the full injury reports for the Buffalo Bills and Jacksonville Jaguars ahead of their Week 3 matchup at Highmark Stadium: Jacksonville Jaguars (0-2) Did not practice TE Evan Engram (hamstring