San Francisco head coach Kyle Shanahan told reporters on Monday that star wide receiver Deebo Samuel will miss “a couple” of weeks with a calf strain sustained in Sunday’s loss to the Vikings. Samuel has 13 catches for 164 yards, plus a rushing touchdown, this season.

Brock Purdy and the San Francisco 49ers took on Aaron Rodgers and the New York Jets on Monday Night Football in their season opener at Levi’s Stadium as they seek to return to the Super Bowl. The 49ers defeated the Jets 32-19, with place kicker Jake Moody putting up six of six field goals for a total of 18 points.

The Los Angeles Rams need a win in the worst way possible this week after dropping to 0-2 on the year with their 41-10 loss

George Kittle missed practice on Thursday because of a hamstring injury. Here's the latest on the TE's status for the Week 3 49ers vs. Rams game.

The San Francisco 49ers could be without another key offensive player this week after All-Pro tight end George Kittle missed practice with a sore hamstring. The Niners are lost All-Pro running back Christian McCaffrey and star receiver Deebo Samuel to injuries before Kittle reported soreness in his hamstring after Wednesday's practice.

George Kittle could have to miss his first game of the season as the San Francisco 49ers take on the Los Angeles Rams on Sunday. Per ESPN's Adam