Jimmy Garoppolo knows what it feels like as a San Francisco 49er to come to L.A., but now the quarterback is on the other ...

George Kittle missed practice on Thursday because of a hamstring injury. Here's the latest on the TE's status for the Week 3 ...

Take a look at some of the San Francisco 49ers best plays versus NFC West opponents of all time. San Francisco 49ers ...

In Week 1, Juszczyk, the wife of San Francisco 49ers fullback Kyle Juszczyk, created one of her custom jackets but with a ...

San Francisco 49ers fullback Kyle Juszczyk goes flying for the games first big play in Super Bowl LVIII on Nickelodeon. Watch the best of the Manning brothers on "Monday Night Football"' during ...

San Francisco 49ers quarterback Brock Purdy's 34-yard loft to fullback Kyle Juszczyk marks the longest play of Jets-49ers so far. San Francisco 49ers quarterback Brock Purdy and wide receiver ...

Sam Darnold passed for 268 yards and two touchdowns against his former team, including a 97-yard strike in the second quarter ...

Listen in as 49ers defensive lineman Javon Hargrave was wired for sound during San Francisco's Week 2 matchup against the ...

While the Vikings started the season strong by trouncing the Giants, they'll face a stiffer test Sunday when the 49ers come ...

Sunday's 23-17 loss to the Minnesota Vikings was a setback for the San Francisco 49ers, who set their sights on winning the Super Bowl this season.

Darnold passed for 268 yards and two touchdowns against his former team, including a 97-yard strike in the second quarter to ...