The Indianapolis Colts need everything they can to defeat the Detroit Lions at Lucas Oil Stadium tomorrow afternoon. While there are plenty of players to highlight in this cross-conference battle, all Colts fans' eyes will be on quarterback Anthony Richardson and whether he can build on a solid week 11 victory.

The Indianapolis Colts are coming off a win over the Jets in what was a highly encouraging performance from Anthony Richardson. However, awaiting them in Week 12 are the red-hot Lions. Detroit will enter this game at 9-1 and have consistently been the most

Preview the Week 12 matchup between the Detroit Lions and Indianapolis Colts with predictions, odds, over/under, spread, betting lines and more.