The 49ers activated running back Christian McCaffrey from injured reserve Saturday, setting up his season debut on Sunday vs.

San Francisco 49ers running back Isaac Guerendo joined the 49ers "You've Got Mail" podcast presented by Delta Dental to discuss his journey to the pros, the early contributions of the rookie class and ...

49ers Open Practice Window for Key OL After ... Three players later, Purdy made a fantastic throw to FB Kyle Juszczyk but a questionable illegal shift ruled it out. Still, the pass is worth ...

The final injury report for the Los Angeles Rams vs Miami Dolphins game on Monday Night Football was released on ...

Is this the week that San Francisco 49ers running back Christian McCaffrey returns? McCaffrey has missed all eight of his ...

Kyle Shanahan ...

Watch the bizarre AI video posted by Jake Paul ahead of his highly anticipated Netflix fight against boxing legend Mike Tyson.

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