Jimmy Garoppolo knows what it feels like as a San Francisco 49er to come to L.A., but now the quarterback is on the other ...

Juszczyk has accumulated 5.9 fantasy points in his two games this year. He has zero carries for zero yards and zero ...

Without changing its identity, Lester has transformed Iowa's offense and helped make Johnson the leading rusher in the FBS.

Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

RAMS:Predictions, picks and odds for NFL Week 3 game Here's what to know about ... Saubert would likely get most of the 49ers' reps if Kittle can't play, but fullback Kyle Juszczyk can't be counted ...

SANTA CLARA, Calif. — The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And ...

On a day the Rams placed safety John Johnson III and offensive lineman Jonah Jackson on the team's seemingly never-ending list of players on injured reserve, the Rams did not take that step with Kupp, ...

Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

Take a look at some of the San Francisco 49ers best plays versus NFC West opponents of all time. San Francisco 49ers ...

The 49ers QB became a better vocal leader this offseason. How will that help him overcome injuries to Deebo Samuel Sr. and ...