San Francisco 49ers George Kittle lost a bet as he was seen wearing UCLA gear while speaking to reporters on Thursday. Kittle ...

The San Francisco 49ers and Seattle Seahawks will face off in a NFC West showdown this Sunday, and if you want to attend the ...

NFL WAG Kristin Juszczyk, the wife of San Francisco 49ers fullback Kyle Juszczyk, showed off her ab-revealing vest and matching skirt fit for a 'date night' on ...

The 49ers are still trying to get over a massive Super Bowl hangover. Leave it to Patrick Mahomes and the Kansas City Chiefs to remind them of the task. San Francisco (3-4) came up short again ...

And, one of their defenders could provide some aid to the San Francisco 49ers. The Niners got back ... Adding to all that, he would come cheap, as he'll likely cost a late Day 3 pick.

Instead, it was the San Francisco 49ers who held on to win, 30-24, in prime time. The 49ers trailed the Cowboys 10-6 at halftime but turned the tide in their favor with three straight touchdown ...

One of the most exciting rivalries reignites this Sunday as Dak Prescott and the Dallas Cowboys face the San Francisco 49ers in a Sunday Night Football showdown. The two teams have gone head-to-head ...

The NFL, on Saturday, announced that it has fined San Francisco ... to take a cheap shot and hit Williams in the head. Williams, in turn, responded by smacking Cook in the head. The 49ers star ...

The San Francisco 49ers have been in this position before ... and they've been known for kicking into gear after slow starts in recent seasons, too. The X-factor for San Francisco this season ...

Kansas City Chiefs quarterback Patrick Mahomes scored his first rushing touchdown in 32 games last week in the Super Bowl rematch against the San Francisco 49ers. During that scamper from a yard ...

After last year's Super Bowl appearance, the San Francisco 49ers were projected as one of the best teams in the NFC. However, they are hurting just as badly as the Cowboys (3-3) since losing to ...